Alt-Data Signal Hub

ANAB

AnaptysBio, Inc. · $53.36 (-3.1%) · mkt cap $1.6B

3 hub catalysts across 1 sources · backtest → · ← Ticker Explorer

SEC EDGAR Filings

Signal summary

Signals diverge

Bullish and bearish forces are in conflict here — weigh both columns.

36 conviction from hub signals

Bullish factors

1 analyst upgrade

Bearish factors

Insiders net selling (12 vs 2)

Best strategy

2-yr backtest · by Sharpe

Golden / Death Cross (50/200) has fit ANAB best over 2 years (+173.7%, Sharpe 1.19). Historical/in-sample — walk-forward all 19 →

#	Strategy	Return	Sharpe	Beats B&H
1	Golden / Death Cross (50/200)	+173.7%	1.19	✓
2	Momentum (rate-of-change)	+148.5%	1.00	✓
3	Buy & Hold (baseline)	+134.9%	0.94

Price — 1 year

daily close

Insider activity

2 open-market buys

Officers & directors trading their own stock (SEC Form 4). Buys are bullish; sells shown for context.

Date	Action	Insider	Shares	Value
2026-03-30	SELL	Schmid John P	20,645	$1.2M
2026-03-27	SELL	Faga Daniel R	17,679	$1.1M
2026-02-11	SELL	Loumeau Eric Joseph	10,000	$540K
2026-01-15	SELL	Marquet Magda	11,000	$531K
2026-01-08	SELL	Mulroy Dennis Cpa	2,515	$112K
2026-01-08	SELL	Faga Daniel R	14,281	$639K
2026-01-08	SELL	Lizzul Paul F.	3,650	$163K
2026-01-08	SELL	Loumeau Eric Joseph	2,210	$99K
2026-01-07	SELL	Mulroy Dennis Cpa	1,908	$86K
2026-01-07	SELL	Faga Daniel R	9,202	$415K
2026-01-07	SELL	Lizzul Paul F.	2,235	$101K
2026-01-07	SELL	Loumeau Eric Joseph	9,639	$439K
2025-01-02	BUY	Ecor1 Capital, L.L.C.	85,098	$1.1M
2024-08-14	BUY	Ecor1 Capital, L.L.C.	273,972	$10.0M

Analyst ratings

live · 2 changes

Date	Action	Analyst	Rating Change
2025-10-13	Initiated	Barclays	Overweight
2025-06-04	Upgrade	HC Wainwright & Co.	Neutral → Buy

Catalyst timeline

3 hub signals

Date	Source	Event	Entity
2026-07-30	SEC EDGAR Filings	8-K Event	ANAPTYSBIO, INC	source ↗
2026-06-22	SEC EDGAR Filings	8-K Event	ANAPTYSBIO, INC	source ↗
2026-05-29	SEC EDGAR Filings	8-K Event	ANAPTYSBIO, INC	source ↗